Structural basis for a nucleoporin exportin complex between RanBP2, SUMO1-RanGAP1, the E2 Ubc9, Crm1 and the Ran GTPase
Vladimir Baytshtok, Michael A. DiMattia, Christopher D. Lima
The paper presents cryo-EM structures of a RanBP2 complex with Crm1, SUMO1-RanGAP1/Ubc9, and Ran(GTP), revealing interactions critical for mitotic progression.
Nature Communications · Jul 11, 2025Peer-reviewedBiochemistry