Author

Vladimir Seplyarskiy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Organism:multiple species· 1 Research Focus:phylogenetics / evolution· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Georgii A Bazykin· 2 shared Maria Andrianova· 1 shared Nadezhda V Terekhanova· 1 shared Ruslan A. Soldatov· 1 shared Sergey Nikolaev· 1 shared

Activity by Year

2016-2016 · peak 2/yr

Co-Author Collaboration Network

5 top collaborators · 6 mutual co-author links

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2 shared papersMolecular Biology

Georgii A Bazykin

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2 papers

Recent·Most cited

Molecular BiologybioRxivMay 22, 2016

Evolution of local mutation rate and its determinants

Nadezhda V Terekhanova, Vladimir Seplyarskiy, Ruslan A. Soldatov, Georgii A Bazykin

The paper compares local mutation rates across species and finds that while some variation is explained by genomic features, much remains unexplained and species-specific.

DOI 10.1093/molbev/msx060

humanmultiple species

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Molecular BiologybioRxivMar 23, 2016

Human mismatch repair system corrects errors produced during lagging strand replication more effectively

Maria Andrianova, Georgii A Bazykin, Sergey Nikolaev, Vladimir Seplyarskiy

The paper investigates human mismatch repair (MMR) efficiency in correcting errors from leading and lagging DNA strands, finding that lagging strand mutations are repaired ~3 times more effectively in MMR-proficient cells.

DOI 10.1101/gr.219915.116

humanDNA methylation

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