Author

W P Guo

Guilin Medical University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Dong Tan· 1 shared Gang FaniD· 1 shared Jing Yang· 1 shared Jingfen Lu· 1 shared Jinhui ZhaiD· 1 shared Miao LiuiD· 1 shared Qingping ZhangiD· 1 shared Yaohui He· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPharmacology & Toxicology

Dong Tan

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1 paper

Recent·Most cited

Potent Efficacy of Computer-Aided Designed Peptide Degrader Drug on PCSK9-Mediated Hypercholesterolemia

Gang Fan, W P Guo, Jingfen Lu, Yaohui He, Jinhui Zha, Qingping Zhang, Yijia Chen, Dong Tan, 唐志晗, Jing Yang, Zhijian Yu, Miao Liu

This study develops a computer-aided designed peptide degrader, Cadd4, which reduces PCSK9 levels and lowers LDL-C in mice and human liver tissue without toxicity.

Metabolism · Dec 24, 2025Peer-reviewedPharmacology & Toxicology