Author

Zhijian Yu

Shenzhen UniversityORCID 0000-0002-9297-8609Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:proteomics· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Dong Tan· 1 shared Gang FaniD· 1 shared Han‐Xiang DengiD· 1 shared Jing Yang· 1 shared Jingfen Lu· 1 shared Jinhui ZhaiD· 1 shared Miao LiuiD· 1 shared Qingping ZhangiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperPharmacology & Toxicology

Dong Tan

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2 papers

Recent·Most cited

Pharmacology & ToxicologyMetabolismPeer-reviewedDec 24, 2025

Potent Efficacy of Computer-Aided Designed Peptide Degrader Drug on PCSK9-Mediated Hypercholesterolemia

Gang Fan, W P Guo, Jingfen Lu…·Miao Liu

This study develops a computer-aided designed peptide degrader, Cadd4, which reduces PCSK9 levels and lowers LDL-C in mice and human liver tissue without toxicity.

6 citations

mousehuman

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MicrobiologyBMC MicrobiologyPeer-reviewedJul 2, 2025

Repurposing AZD-5991 for inhibiting growth and biofilm formation of Staphylococcus aureus by disrupting the cell membrane and targeting FabI.

Yuanyuan Tang, Han‐Xiang Deng, Zhichao Xu…·Tieying Hou

This paper shows AZD-5991 inhibits S. aureus growth and biofilm formation by disrupting the cell membrane and targeting FabI, suggesting it as a potential new antibiotic.

4 citations

humanproteomics

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