Cardiomyopathy Mutations Impact the Power Stroke of Human Cardiac Myosin
W. Tang, J. Ge, W. C. Unrath, R. Desetty, C. M. Yengo
This study investigates how cardiomyopathy mutations affect the power stroke of human cardiac myosin using FRET and kinetic measurements, revealing impaired structural changes and reduced force development.
bioRxiv · Dec 8, 2020Biophysics