Spatial transcriptomic analysis drives PET imaging of tight junction protein expression in pancreatic cancer theranostics
J. Wang, J. W. Seo, A. J. Kare, M. Schneider, S. K. Tumbale, B. Wu, M. N. Raie, M. Pandrala, A. Iagaru, R. L. Brunsing, G. W. Charville, W. G. Park, K. W. Ferrara
The paper uses spatial transcriptomics and proteomics to identify claudin-4 as a theranostic target in pancreatic cancer, showing its increased expression and suitability for molecular imaging.
bioRxiv · Jan 7, 2024 · PreprintBioengineering