Conformational specificity of opioid receptors is determined by subcellular location irrespective of agonist
S. E. Crilly, W. Ko, Z. Y. Weinberg, M. A. Puthenveedu
This study shows that the same opioid receptor agonist induces different conformational states of the delta-opioid receptor depending on its subcellular location, leading to distinct effector coupling.
bioRxiv · Mar 18, 2021Cell Biology