Compartment-Specific Activation of the Proton-Sensor GPR65 is Uncoupled from Receptor Trafficking
L. M. Morales Rodriguez, S. E. Crilly, J. Rowe, D. G. Isom, M. A. Puthenveedu
This study shows that GPR65, a proton-sensor GPCR, is constitutively active in endosomes and its signaling is uncoupled from receptor trafficking.
bioRxiv · Mar 18, 2023 · PreprintPharmacology & Toxicology