Selective whole-genome sequencing of Plasmodium parasites directly from blood samples by Nanopore adaptive sampling
K. De Meulenaere, W. L. Cuypers, A. Rosanas-Urgell, K. Laukens, B. Cuypers
This study demonstrates that adaptive Nanopore sequencing can effectively enrich for Plasmodium DNA in blood samples, achieving sufficient coverage for drug resistance variant detection.
bioRxiv · Nov 29, 2022Microbiology