Author

B. Cuypers

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:proteomics· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Approach:machine learning (classical)· 2 Organism:mouse· 2

Frequent Co-Authors

K. Laukens· 5 shared P. Meysman· 3 shared A. Hefnawy· 1 shared A. Mrzic· 1 shared A. Rosanas-Urgell· 1 shared A. Suls· 1 shared A. van Rie· 1 shared B. Ogunjimi· 1 shared

Activity by Year

2017-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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5 shared papersMicrobiology

K. Laukens

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Predicting MmpR-based bedaquiline resistance using sequence- and structure-based features

E. Riviere, M. Safarpour, P. Meysman, B. Cuypers, C. Meehan, K. Laukens, A. van Rie

This paper develops a machine learning model to predict bedaquiline resistance using sequence and structural features of Rv0678 variants, achieving moderate performance but not sufficient for clinical use.

bioRxiv · Dec 19, 2022 · PreprintMicrobiology

Selective whole-genome sequencing of Plasmodium parasites directly from blood samples by Nanopore adaptive sampling

K. De Meulenaere, W. L. Cuypers, A. Rosanas-Urgell, K. Laukens, B. Cuypers

This study demonstrates that adaptive Nanopore sequencing can effectively enrich for Plasmodium DNA in blood samples, achieving sufficient coverage for drug resistance variant detection.

bioRxiv · Nov 29, 2022Microbiology

Investigating the Role of Chromatin Remodeler FOXA1 in Ferroptotic Cell Death

E. Logie, L. Maes, J. Van Meenen, P. H. De Rijk, M. Strazisar, G. Joris, B. Cuypers, K. Laukens, W. V. Berghe

This study investigates the role of FOXA1 in ferroptotic cell death in multiple myeloma cells, finding that FOXA1 is upregulated and binds to pericentromeric regions during ferroptosis.

bioRxiv · Oct 13, 2021 · PreprintCancer Biology

Predicted epitope binding core motifs and common amino acid polymorphisms distinguish protective- from susceptibility-associated HLA alleles in leishmaniasis

N. de Vrij, P. Meysman, S. Gielis, W. Adriaensen, K. Laukens, B. Cuypers

bioRxiv · Feb 19, 2021Immunology

Genomic and phenotypic characterization of experimentally selected resistant Leishmania donovani reveals a role for dynamin-1 like protein in the mechanism of resistance to a novel anti-leishmanial compound

A. Hefnawy, G. Negreira, M. Jara, J. A. Cotton, I. Maes, E. D'Haenens, H. Imamura, B. Cuypers, P. Monsieurs, C. Mouchtoglou, H. De Winter, M. Berriman, M. Sanders, J. Martin, G. De Muylder, , M. A. Domagalska

This study experimentally selects resistance to a novel anti-leishmanial compound in Leishmania donovani and identifies mutations in the dynamin-1-like protein as a key mechanism of resistance.

bioRxiv · Jan 5, 2021Microbiology

On the feasibility of mining CD8+ T-cell receptor patterns underlying immunogenic peptide recognition.

N. De Neuter, W. Bittremieux, C. Beirnaert, B. Cuypers, A. Mrzic, P. Moris, A. Suls, V. Van Tendeloo, B. Ogunjimi, K. Laukens, P. Meysman

The paper develops a random forest classifier to predict T-cell receptor recognition of peptides and identifies structural CDR3 features associated with immunogenicity.

bioRxiv · Mar 20, 2017Immunology