Mapping Single-molecule Protein Complexes in 3D with DNA Nanoswitch Calipers
P. Shrestha, D. Yang, W. M. Shih, W. P. Wong
The paper introduces a method to map 3D geometries of single-molecule protein complexes with high resolution using DNA Nanoswitch Calipers and force-based barcoding, achieving agreement with known structures.
bioRxiv · Jul 10, 2023Biophysics