Author

W. P. Wong

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:proteomics· 3 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

D. Yang· 5 shared A. R. Chandrasekaran· 1 shared A. Ward· 1 shared B. Wu· 1 shared C. H. Hansen· 1 shared D. Mathis· 1 shared D. P. Corey· 1 shared E. Greenwald· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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5 shared papersBiophysics

D. Yang

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Mapping Single-molecule Protein Complexes in 3D with DNA Nanoswitch Calipers

P. Shrestha, D. Yang, W. M. Shih, W. P. Wong

The paper introduces a method to map 3D geometries of single-molecule protein complexes with high resolution using DNA Nanoswitch Calipers and force-based barcoding, achieving agreement with known structures.

bioRxiv · Jul 10, 2023Biophysics

DNA nanoswitch barcodes for multiplexed biomarker profiling

A. R. Chandrasekaran, M. MacIsaac, J. Vilcapoma, C. H. Hansen, D. Yang, W. P. Wong, K. Halvorsen

This paper introduces DNA nanoswitch barcodes for multiplexed detection of up to 6 biomarkers in a single assay, demonstrating mixed multiplexing of DNA, RNA, antibody, and protein.

bioRxiv · Sep 22, 2020Bioengineering

Dual functions of Aire CARD multimerization in the transcriptional regulation of T cell tolerance

Y.-S. Huoh, B. Wu, S. Park, D. Yang, K. Bansal, E. Greenwald, W. P. Wong, D. Mathis, S. Hur

This study shows that Aire's CARD-mediated multimerization forms nuclear foci and affects transcriptional activity, but also increases susceptibility to PML body interactions, which can impair its function.

bioRxiv · Feb 26, 2020Immunology

Stretching DNA to twice the normal length with single-molecule hydrodynamic trapping

Y. Jiang, T. Feldman, J. A. M. Bakx, D. Yang, W. P. Wong

This paper introduces a new single-molecule force spectroscopy method that stretches DNA to twice its normal length under high tension.

bioRxiv · Jan 15, 2020Biophysics

The Dynamic Strength of the Hair-Cell Tip Link Reveals Mechanisms of Hearing and Deafness

E. M. Mulhall, A. Ward, D. Yang, M. A. Koussa, D. P. Corey, W. P. Wong

This paper measures the dynamic mechanical properties of hair-cell tip links, revealing their role in hearing and deafness through single-molecule analysis.

bioRxiv · Sep 12, 2019Biophysics