StemBond hydrogels optimise the mechanical microenvironment for embryonic stem cells
C. Labouesse, C. C. Agley, B. X. Tan, M. Hofer, A. Winkel, G. G. Stirparo, H. T. Stuart, C. M. Verstreken, W. Mansfield, P. Bertone, K. Franze, J. C. R. Silva, K. J. Chalut
This study develops StemBond hydrogels that independently control substrate stiffness and ECM tethering, showing they enhance ES cell self-renewal and reprogramming efficiency.
bioRxiv · Sep 13, 2019 · PreprintCell Biology