Chemical Inhibitors of DksA1, a Conserved Bacterial Transcriptional Regulator, Suppressed Quorum Sensing-Mediated Virulence in Pseudomonas aeruginosa
K. B. Min, W. T. Hwang, K.-M. Lee, S. S. Yoon
This study identifies two chemical inhibitors of DksA1 that suppress quorum sensing-mediated virulence in Pseudomonas aeruginosa, reducing virulence factors and increasing antibiotic susceptibility.
bioRxiv · Dec 10, 2020Microbiology