Live-Cell Tracking of γ-H2AX Kinetics Reveals the Distinct Modes of ATM and DNA-PK in Immediate Response to DNA Damage
W. Trakarnphornsombat, H. Kimura
This study uses live-cell imaging to compare ATM and DNA-PK phosphorylation of H2AX after DNA damage, finding that DNA-PK acts rapidly while ATM shows dynamic chromatin binding.
bioRxiv · Oct 9, 2022Cell Biology