Structural insights into substrate recognition by the SOCS2 E3 ubiquitin ligase
W.-W. Kung, S. Ramachandran, N. Makukhin, E. Bruno, A. Ciulli
This study determines the structure of SOCS2 bound to phosphorylated peptides, revealing substrate recognition mechanisms and implications for ligand design.
bioRxiv · Mar 15, 2019Biochemistry