Author

N. Makukhin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Assay:cryo-EM· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Ciulli· 2 shared C. Crowe· 1 shared E. Bruno· 1 shared M. H. Tatham· 1 shared M. Nakasone· 1 shared R. T. Hay· 1 shared S. Chandler· 1 shared S. Ramachandran· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 21 mutual co-author links

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2 shared papersBiochemistry

A. Ciulli

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2 papers

Recent·Most cited

Mechanism of degrader-targeted protein ubiquitinability

C. Crowe, M. Nakasone, S. Chandler, M. H. Tatham, N. Makukhin, R. T. Hay, A. Ciulli

The paper solves cryo-EM structures of a degrader-mediated complex to reveal structural insights into target protein ubiquitination mechanisms.

bioRxiv · Feb 5, 2024Biochemistry

Structural insights into substrate recognition by the SOCS2 E3 ubiquitin ligase

W.-W. Kung, S. Ramachandran, N. Makukhin, E. Bruno, A. Ciulli

This study determines the structure of SOCS2 bound to phosphorylated peptides, revealing substrate recognition mechanisms and implications for ligand design.

bioRxiv · Mar 15, 2019Biochemistry