GeneticsbioRxivPreprint
Deletion of the CTG Expansion in Myotonic Dystrophy Type 1 Reverses DMPK Aberrant Methylation in Human Embryonic Stem Cells but not Affected Myoblasts
Shira Yanovsky‐Dagan, Ester Bnaya, Manar Abu Diab…·Rachel Eiges
This study shows that deleting the CTG expansion in DM1 hESCs reverses DMPK methylation and restores SIX5 transcription, but has no effect on affected myoblasts.
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