Defective cell death of distinct microglial subsets contributes to ADHD-like behavior in mice
Hsiu‐Chun Chuang, Eva K. Nichols, Isabella Rauch, Wei-Cheng Chang, Rhea Misra, Patrick M. Lin, Maiko Kitaoka, Russell E. Vance, Kaoru Saijo
The paper shows that defective microglial pyroptosis in mice leads to ADHD-like behaviors, suggesting a link between microglial cell death and neurodevelopmental disorders.
bioRxiv · Aug 30, 2019 · PreprintNeuroscience