Rapid CD4 cell loss is caused by specific CRF01_AE cluster with V3 signatures favoring CXCR4 usage
Hongshuo Song, Weidong Ou, Yi Feng, Junli Zhang, Fan Li, Jing Hu, Hong Peng, Hui Xing, Liying Ma, Qiuxiang Tan, Beili Wu, Yiming Shao
The paper identifies a specific CRF01_AE HIV-1 phylogenetic cluster associated with rapid CD4 cell loss and higher prevalence of CXCR4-using viruses.
bioRxiv · Sep 26, 2018 · PreprintMicrobiology