Altered transcription factor binding events predict personalized gene expression and confer insight into functional cis-regulatory variants
Wenqiang Shi, Oriol Fornés, Wyeth W. Wasserman
The paper introduces TF2Exp, a framework predicting gene expression impact from cis-regulatory variants by modeling altered transcription factor binding, showing comparable performance to SNP-based models.
Bioinformatics · Dec 10, 2018Peer-reviewedBioinformatics