ImmunologybioRxivPreprint
Cis-delivering releasable IL-15 superagonist enhances antitumor immunity in cold tumors by invigorating preexisting CD25+CD8+ T cells
Qiongya Zeng, Wencheng Kong, Ying Qin…·Huili Lu
This study develops a releasable IL-15 superagonist that enhances antitumor immunity in cold tumors by activating CD25+CD8+ T cells while reducing toxicity.
DOI 10.1101/2025.08.14.670432