KLF7-Regulated ITGA2 as a Therapeutic Target for Inhibiting Oral Cancer Stem Cells
Xin Qi, Zhou Jiang, Pan Wang, Yunyan Li, Haoran Li, Yuwen Miao, Xiaoqing Ma, Xiayan Luo, Zhiling Zhang, Yanling He, Wenyi Shen, Wenquan Zhao, Rutao Cui, Cang Li, Huiyong Zhu, Jiong Lyu
This study identifies ITGA2 as a therapeutic target regulated by KLF7 that sustains oral cancer stemness and drug resistance through interactions with collagen and activation of stemness pathways.
Cell Death and Disease · May 2, 2025Peer-reviewedCancer Biology