A human-in-the-loop explanation framework for morphologically transparent AI predictions from whole-slide images
Peiliang Lou, Yitan Zhu, Nicholas Chia, Roopa Kumari, William Yang, Yan Wang, Brenna C. Novotny, Stacey J. Winham, Ruifemg Guo, Ellen L. Goode, Yajue Huang, Wenchao Han, Tianshu Feng, Chen Wang
This paper introduces MorphoXAI, a human-in-the-loop framework for explaining AI predictions on whole-slide images, showing it provides accurate and interpretable histomorphological explanations at both global and local levels.
npj Digital Medicine · May 14, 2026Peer-reviewedPathology