Ellen L. Goode

This paper introduces MorphoXAI, a human-in-the-loop framework for explaining AI predictions on whole-slide images, showing it provides accurate and interpretable histomorphological explanations at both global and local levels.

This study uses exome sequencing to identify HELB as a novel susceptibility gene for non-high grade serous epithelial ovarian cancer, with a strong association found in genetic analyses.

This study identifies 135 genomic loci associated with venous thromboembolism risk through cross-ancestry GWAS and provides insights into biological pathways and potential therapeutic targets.

This study improves transcriptome-wide association studies by integrating pleiotropy-guided methods with GWAS data to identify new cancer susceptibility genes.

This study assesses polygenicity and risk prediction using common variants across 14 cancers, finding varying numbers of susceptibility variants and risk score effectiveness.

This study combines genome-wide association data from four cancers to identify shared and novel genetic associations and pleiotropic effects.