Tree reconstruction guarantees from CRISPR-Cas9 lineage tracing data using Neighbor-Joining
Sebastian Prillo, Kevin An, Wilson Wu, Ivan Kristanto, Matthew G. Jones, Yun S. Song, Nir Yosef
This paper develops a Neighbor-Joining algorithm with theoretical guarantees for reconstructing phylogenies from CRISPR-Cas9 lineage tracing data, showing improved performance on simulated and real data.
bioRxiv · Aug 27, 2024 · PreprintBioinformatics