Author

Wolfgang M.J. Obermann

University of Cologne

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Developmental Biology· 1

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Organism:human· 1 Organism:mouse· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1 Organism:zebrafish· 1

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Dörte Schulte-OstermanniD· 1 shared Fabian MetzeniD· 1 shared J. Fernando BazániD· 1 shared Jörg StetefeldiD· 1 shared Katharina UphoffiD· 1 shared Manuel KochiD· 1 shared Matthias MörgeliniD· 1 shared Melina HußmanniD· 1 shared

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Dörte Schulte-OstermannORCID

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1 paper

Recent·Most cited

Developmental BiologyeLifePeer-reviewedOct 30, 2026

SVEP1 enables efficient binding of Angiopoietin-2 to the TIE1 receptor, allowing receptor phosphorylation and downstream signaling

Katharina Uphoff, Melina Hußmann, Oliver Peters…·Dörte Schulte-Ostermann

This study identifies SVEP1 as a mediator of ANG2-TIE1 binding, leading to TIE1 phosphorylation and downstream signaling in lymphatic endothelial cells.

DOI 10.7554/elife.106338.3

humanmouse

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