Author

Fabian Metzen

University of CologneORCID 0000-0002-5248-8218Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Manuel KochiD· 2 shared Andrew A. PitsillidesiD· 1 shared Anja NiehoffiD· 1 shared Bent BrachvogeliD· 1 shared David E. BirkiD· 1 shared Dörte Schulte-OstermanniD· 1 shared Gudrun SchreiberiD· 1 shared J. Fernando BazániD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersDevelopmental Biology

Manuel KochORCID

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2 papers

Recent·Most cited

Developmental BiologyeLifePeer-reviewedOct 30, 2026

SVEP1 enables efficient binding of Angiopoietin-2 to the TIE1 receptor, allowing receptor phosphorylation and downstream signaling

Katharina Uphoff, Melina Hußmann, Oliver Peters…·Dörte Schulte-Ostermann

This study identifies SVEP1 as a mediator of ANG2-TIE1 binding, leading to TIE1 phosphorylation and downstream signaling in lymphatic endothelial cells.

DOI 10.7554/elife.106338.3

humanmouse

GeneticsbioRxivPreprintDec 29, 2021

Ablation of the FACIT collagen XII disturbs musculoskeletal ECM organization and causes patella dislocation and myopathy

Mengjie Zhu, Fabian Metzen, Janina Betz…·Bent Brachvogel

This study shows that collagen XII deficiency in mice causes patella dislocation and myopathy, with altered gene expression in tenocytes and human patients showing similar patella instability.

DOI 10.1101/2021.12.29.474475

mousebulk RNA-seq