Bcl-xL inhibition enhances Dinaciclib-induced cell death in soft-tissue sarcomas.
S. Rello-Varona, M. Fuentes-Guirado, R. Lopez-Alemany, A. Contreras-Perez, N. Mulet-Margalef, S. Garcia-Monclus, O. M. Tirado, X. Garcia del Muro
This study shows that Bcl-xL inhibition enhances Dinaciclib-induced cell death in soft-tissue sarcomas by targeting the mitochondrial apoptosis pathway.
bioRxiv · Sep 17, 2018Cancer Biology