The creation and selection of mutations resistant to a gene drive over multiple generations in the malaria mosquito
A. M. Hammond, K. Kyrou, M. Bruttini, A. North, R. Galizi, X. Karlsson, F. Carpi, R. D'Aurizio, A. Crisanti, T. Nolan
This study tracks the emergence of resistance mutations in a gene drive targeting malaria mosquitoes over 25 generations, showing positive selection for resistance.
bioRxiv · Jun 12, 2017Evolutionary Biology