Author

X. S. Li

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Immunology· 1

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Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

C. Guo· 1 shared M. ZHAO· 1 shared P. Zhu· 1 shared X. Sui· 1 shared Z. Balsara· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperImmunology

C. Guo

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1 paper

Recent·Most cited

The PRC2-dependent epigenetic reprograming of the bladder epithelium exacerbates urinary tract infections

C. Guo, M. ZHAO, X. Sui, Z. Balsara, P. Zhu, X. S. Li

This study shows that PRC2-dependent epigenetic reprogramming in bladder urothelium worsens UTIs by promoting inflammation and impaired differentiation, and that inhibiting Ezh2 can improve disease outcomes.

bioRxiv · Oct 22, 2020 · PreprintImmunology