Author

X. S. Wang

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Biology Disciplines

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Biochemistry· 1

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Approach:biophysical modeling· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

B. C. Lechtenberg· 1 shared J. Silke· 1 shared L. W. Richardson· 1 shared S. J. Trevelyan· 1 shared T. R. Cotton· 1 shared W. T. Lee· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperBiochemistry

B. C. Lechtenberg

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1 paper

Recent·Most cited

The unifying catalytic mechanism of the RING-between-RING E3 ligase family

X. S. Wang, T. R. Cotton, S. J. Trevelyan, L. W. Richardson, W. T. Lee, J. Silke, B. C. Lechtenberg

This study defines the core catalytic mechanism of RBR E3 ligases through structural and biochemical analysis of HOIL-1 and RNF216, revealing conserved features and an allosteric mechanism.

bioRxiv · Oct 11, 2022Biochemistry