Author

X. Shirley Liu

Dana-Farber Cancer Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Bioinformatics· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Organism:human· 2 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Bo LiiD· 1 shared Changxin WaniD· 1 shared Clifford A. MeyeriD· 1 shared Daniel Fernandez· 1 shared Gali BaiiD· 1 shared Hanfei Sun· 1 shared Heng LiiD· 1 shared Jiexing Wu· 1 shared

Activity by Year

2015-2023 · peak 1/yr

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10 top collaborators · 14 mutual co-author links

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1 shared paperBioinformatics

Bo LiORCID

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3 papers

Recent·Most cited

BioinformaticsGenome ResearchPeer-reviewedJun 1, 2023

T1K: efficient and accurate KIR and HLA genotyping with next-generation sequencing data

Li Song, Gali Bai, X. Shirley Liu…·Heng Li

T1K is a computational method for accurately inferring KIR and HLA alleles from next-generation sequencing data, showing enrichment of KIR2DL4 in tumor-specific CD8+ T cells.

54 citations

humanbulk RNA-seq

𝕏 PostBluesky

BioinformaticsGenome biologyPeer-reviewedFeb 7, 2020

Inferring transcriptional regulators through integrative modeling ofpublic chromatin accessibility and ChIP-seq data

Qian Qin, Jing‐Yu Fan, Rongbin Zheng…·X. Shirley Liu

Lisa predicts transcriptional regulators of gene sets by integrating chromatin accessibility and ChIP-seq data to identify relevant regulators.

296 citationstop 1%

ChIP-seqDNA methylation

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GeneticsbioRxivPreprintMar 22, 2015

Exploring functional variation affecting ceRNA regulation in humans

Mulin Jun Li, Jiexing Wu, Peng Jiang…·X. Shirley Liu

The paper identifies genetic variations affecting ceRNA regulation by analyzing RNA-seq data and GWAS results, revealing new regulatory mechanisms and disease associations.

DOI 10.1101/016865

humanbulk RNA-seq

𝕏 PostBluesky