The D614G mutation of SARS-CoV-2 spike protein enhances viral infectivity
J. Hu, C. L. He, Q. Gao, G. J. Zhang, X. X. Cao, Q. X. Long, H. J. Deng, L. Y. Huang, J. Chen, K. Wang, N. Tang, A. L. Huang
This study shows the D614G mutation in SARS-CoV-2 spike protein increases viral infectivity and is more susceptible to elastase cleavage, with minimal impact on neutralizing antibody efficacy.
bioRxiv · Jun 20, 2020 · PreprintMicrobiology