A novel bivalent interaction mode underlies a non-catalytic mechanism for Pin1-mediated Protein Kinase C regulation
X.-R. Chen, K. Dixit, Y. Yang, M. I. McDermott, H. T. Imam, V. A. Bankaitis, T. I. Igumenova
This paper shows Pin1 regulates PKC through a non-catalytic mechanism by binding its C-terminal tail via a novel bivalent interaction mode.
bioRxiv · Sep 18, 2023Biophysics