A mutation in the endonuclease domain of mouse MLH3 reveals novel roles for MutLγ during crossover formation in meiotic prophase I
Melissa Toledo Licourt, Xianfei Sun, Miguel A. Brieño‐Enríquez, Vandana Raghavan, Stephen Gray, Jeffrey Pea, Carolyn R. Milano, Anita Venkatesh, Lekha Patel, P. Borst, Eric Alani, Paula E. Cohen
This paper shows that a mutation in the endonuclease domain of MLH3 in mice disrupts crossover formation during meiosis but allows partial CO generation compared to a full null mutation.
PLoS Genetics · Jun 6, 2019Peer-reviewedGenetics