Jeffrey Pea

This study identifies PCSK5A and GDF9 as key regulators of cumulus-oocyte-complex matrix integrity and cumulus cell migration during late ovulation, with implications for fertility therapeutics.

This study screens compounds to identify those that block meiotic progression in mouse oocytes, offering potential non-hormonal contraceptive candidates.

This study maps the spatiotemporal profile of ovulation in mice using single-cell RNA-seq and spatial transcriptomics, identifying cell state markers and interactions involved in the process.

This paper shows that a mutation in the endonuclease domain of MLH3 in mice disrupts crossover formation during meiosis but allows partial CO generation compared to a full null mutation.