Xiangyu Liu

Automatically Defining Protein Words for Diverse Functional Predictions Based on Attention Analysis of a Protein Language Model

The paper introduces a toolkit using protein language models to define 'protein words' for functional prediction, outperforming motif-based methods across multiple tasks.

Loss of Insulin Signaling in Microglia Impairs Cellular Uptake of Aβ and Neuroinflammatory Response Exacerbating Alzheimer-like Neuropathology

This study shows that loss of insulin signaling in microglia impairs Aβ uptake and neuroinflammatory response, leading to increased Alzheimer-like pathology.