Parkinson's Disease-Linked Kir4.2 Mutation R28C Leads to Loss of Ion Channel Function
Xiaoyi Chen, Rocio K. Finol‐Urdaneta, Mo Chen, Alex M. Sykes, Bingmiao Gao, Jamila Iqbal, David J. Adams, George D. Mellick, Linlin Ma
This study investigates the impact of the Kir4.2R28C mutation on channel function and cellular processes, finding it causes loss of function and disrupts protein stability and trafficking.
The Journal of Physiology · Jun 1, 2025Peer-reviewedCell Biology