Author

Xin Wu

First Affiliated Hospital of Soochow University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Genomics· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:scRNA-seq· 2 Assay:spatial transcriptomics· 2 Research Focus:benchmarking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Alash’le AbimikuiD· 2 shared Aminu Musa· 2 shared Anna WintersiD· 2 shared Chenfeng XiongiD· 2 shared Cheryl BaxteriD· 2 shared Christina RileyiD· 2 shared Daniel J. van ZyliD· 2 shared Danilo Silva· 2 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenomics

Alash’le AbimikuORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Myasthenia thymus reprograms class switched B cells into BAFF dependent survivors

Yuanqing Yan, Diego M. Avella Patino, Yimeng Zhao, Xin Wu, G. R. Scott Budinger, Ankit Bharat

The paper identifies a tolerance checkpoint swap in myasthenia gravis where B cells shift from T cell-dependent activation to BAFF-driven survival, offering new therapeutic targets.

Science Advances · Aug 12, 2026Peer-reviewedGenomics

A Single-Cell and Spatial Atlas of MVP-PAN Evolution Reveals a Desmoplastic Dependency to Overcome Glioblastoma Resistance

Fang Wang, Xin Wu, Guozheng Zhao, Run Huang, Chen Yang, Yu Bai, Wenqian Cao, Yue Lu, Yue Lu, Haohao Qiu, Hongyi Ling, Dengfeng Lu, Youjia Qiu, Juyi Zhang, Bixi Gao, , Zhong Wang

The paper constructs a single-cell and spatial atlas of glioblastoma resistance, identifying a 'Spatial Resistance Triad' and demonstrating that targeting stromal components can overcome therapeutic resistance.

bioRxiv · Jun 17, 2026 · PreprintCancer Biology

Alignment Free Viral Sequence Classification

Daniel J. van Zyl, Marcel Dunaiski, Houriiyah Tegally, Cheryl Baxter, Túlio de Oliveira, Joicymara Santos Xavier, Christina Riley, Anna Winters, Vivek Naranbhai, Felix Made, Salim Abdool Karim, Kennedy Otwombe, Alash’le Abimiku, Sophia Osawe, James Onyemata, , Xin Wu

This study evaluates alignment-free methods for viral sequence classification, showing high accuracy and efficiency on SARS-CoV-2, dengue, and HIV datasets.

BMC Genomics · Apr 18, 2025Peer-reviewedGenomics

Craft: A Machine Learning Approach to Dengue Subtyping

Daniel J. van Zyl, Marcel Dunaiski, Houriiyah Tegally, Cheryl Baxter, Túlio de Oliveira, Joicymara Santos Xavier, Christina Riley, Anna Winters, Vivek Naranbhai, Felix Made, Salim S. Abdool Karim, Kennedy Otwombe, Alash’le Abimiku, Sophia Osawe, James Ezenwa Onyemata, , Xin Wu

Craft is a machine learning framework for dengue subtyping that achieves high accuracy and speed, outperforming existing tools in classification efficiency.

Bioinformatics Advances · Dec 26, 2024Peer-reviewedGenomics