Author

Yu Bai

Soochow UniversityORCID 0000-0002-3661-1968Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Yu Bai2 papers · California State University, Fullerton

Biology Disciplines

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Cancer Biology· 2 Plant Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:deep learning· 2 Organism:human· 2 Assay:scRNA-seq· 2 Research Focus:spatial domain detection· 2 Assay:spatial transcriptomics· 2 Approach:statistical model· 2 Organism:Arabidopsis· 1

Frequent Co-Authors

Bixi GaoiD· 2 shared Dengfeng LuiD· 2 shared Haohao Qiu· 2 shared Juyi Zhang· 2 shared Wenqian Cao· 2 shared Yanbo YangiD· 2 shared Zhouqing CheniD· 2 shared Brian J. StaskawicziD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersCancer Biology

Bixi GaoORCID

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3 papers

Recent·Most cited

A Single-Cell and Spatial Atlas of MVP-PAN Evolution Reveals a Desmoplastic Dependency to Overcome Glioblastoma Resistance

Fang Wang, Xin Wu, Guozheng Zhao, Run Huang, Chen Yang, Yu Bai, Wenqian Cao, Yue Lu, Yue Lu, Haohao Qiu, Hongyi Ling, Dengfeng Lu, Youjia Qiu, Juyi Zhang, Bixi Gao, , Zhong Wang

The paper constructs a single-cell and spatial atlas of glioblastoma resistance, identifying a 'Spatial Resistance Triad' and demonstrating that targeting stromal components can overcome therapeutic resistance.

bioRxiv · Jun 17, 2026 · PreprintCancer Biology

Lineage Memory and Convergent Adaptation Dictate the Single-Cell and Spatial Architecture of Brain Malignancies

Fei Wang, Xiaodong Pang, C Yang, R J Huang, Wenqian Cao, Yu Bai, Haohao Qiu, Juyi Zhang, Bixi Gao, Chao Ma, Yanbo Yang, S M Yang, Dengfeng Lu, Zhouqing Chen, Xiaoou Sun, Zhong Wang

This study constructs the largest single-cell atlas of brain malignancies, revealing lineage memory, convergent adaptation, and spatial architecture shaping tumor microenvironments and clinical outcomes.

bioRxiv · Jun 16, 2026 · PreprintCancer Biology

Switch of TIR signaling by a Ca2+ sensor activates ADR1 recognition of pRib-AMP-EDS1-PAD4 for stomatal immunity

Hanling Wang, Jiaxin Tan, Xiulin Cui, Yu Bai, Shang Gao, Brian J. Staskawicz, Susheng Song, Chuangye Yan, Tiancong Qi

This study identifies a Ca2+ sensor/TIR-only node that links PRR signaling to NLRs by repressing and de-repressing STIR1 function, enabling ADR1 recognition of pRib-AMP-EDS1-PAD4 for stomatal immunity.

bioRxiv · Oct 29, 2024 · PreprintPlant Biology