Calnexin mediates the maturation of GPI-anchors through ER retention
Xin-Yu Guo, Yi-Shi Liu, Xiao-Dong Gao, Taroh Kinoshita, Morihisa Fujita
This study shows calnexin retains GPI-APs in the ER for proper folding and GPI-inositol deacylation, preventing their misfolding and improper surface expression.
bioRxiv · Jul 8, 2020Cell Biology