Author

Xinyue Zhu

Central China Normal University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Bioengineering· 1 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1 Organism:zebrafish· 1

Frequent Co-Authors

Adrian NajeriD· 1 shared Beyzanur KayaiD· 1 shared Fotoula Koropouli· 1 shared Hao SuniD· 1 shared Hongxuan Cao· 1 shared Issabelle WongiD· 1 shared Jian Wan· 1 shared Jonathan C. BrowniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioengineering

Adrian NajerORCID

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2 papers

Recent·Most cited

Antiviral Sulfonated Polymersomes Inhibit Corona-, Influenza-, and Alphavirus

Sinead McCabe, Ruiqi Zhu, Raag Yagnik Setia, Jonathan C. Brown, Ziyi Pan, Xinyue Zhu, Xiaohao Xu, Beyzanur Kaya, Issabelle Wong, Fotoula Koropouli, Pedro S. Londoño, Kai Yi Mok, Ruthiran Kugathasan, Omar Rifaie‐Graham, Vincenzo Torraca, , Adrian Najer

This study designs sulfonated polymersomes that inhibit multiple viruses by targeting host cell receptors, showing potent in vitro and in vivo antiviral activity.

bioRxiv · Oct 11, 2026 · PreprintBioengineering

DeepDOX1: A Dual-Drive Framework Integrating Deep Learning and First-Principles Physics for Drug-Protein Affinity Prediction

Zheng Liu, Hao Sun, Yuliang Wang, Yanliang Ren, Li Rao, Zeyue Huang, Hongxuan Cao, Xiaohong Hu, Xinyue Zhu, Meng Li, Jian Wan

DeepDOX1 integrates deep learning and quantum mechanics to predict drug-protein affinity, outperforming existing models in real-world and challenging drug design scenarios.

bioRxiv · Dec 15, 2025 · PreprintBioinformatics