Single-cell atlas of pig-to-monkey kidney xenotransplantation reveals macrophage chimerism and an IFN-ε orchestrated graft protective immune niche
Hanfeng Wang, James Chen, Yuan Chang, 慈维敏, Xiumeng Hua, Fei Yu, Shujun Yang, Xu Zhang, Jiangping Song, Yang Fan
This study creates a single-cell atlas of pig-to-monkey kidney xenotransplantation, identifying macrophage chimerism and an IFN-ε-driven immune niche that protects the graft.
bioRxiv · Mar 24, 2026 · PreprintGenomics