Mechanism of RSL3-Induced Ferroptotic Cell Death in HT22 Cells: Contributing Role of Protein Disulfide Isomerase
Ming‐Jie Hou, Xuanqi Huang, Bao Ting Zhu
This study shows RSL3 induces ferroptosis in HT22 cells by inhibiting TrxR1, activating PDI, and promoting NOS dimerization and NO accumulation.
Acta Biochimica et Biophysica Sinica · Sep 11, 2024Peer-reviewedCell Biology