Genotype Imputation and Reference Panel: A Systematic Evaluation
Wei-Yang Bai, Xiao-Wei Zhu, Peikuan Cong, Xue-Jun Zhang, John Brent Richards, Hou‐Feng Zheng
The paper evaluates genotype imputation accuracy across Han Chinese and European populations using 394 reference panels, finding optimal diversity levels and highlighting the need for better Chinese reference panels.
bioRxiv · May 19, 2019 · PreprintBioinformatics