Author

Xueying Mao

Shanghai Jiao Tong University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 3

Signature Assays, Organisms & Methods

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Approach:deep learning· 3 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:graph neural network· 1 Organism:human· 1 Assay:protein sequence· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Dong‐Qing WeiiD· 3 shared Heqi SuniD· 2 shared Hong‐Zhou TaniD· 2 shared Junwei CheniD· 2 shared Shenggeng LiniD· 2 shared Yi XiongiD· 2 shared Yufang ZhangiD· 2 shared Bowen ZhaoiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersBioinformatics

Dong‐Qing WeiORCID

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3 papers

Recent·Most cited

ProStab: Prediction of protein stability change upon mutations by protein language and inverse folding models

Hong‐Zhou Tan, Xiaowei Wei, Shenggeng Lin, Xueying Mao, Junwei Chen, Heqi Sun, Yufang Zhang, Zhenghong Zhou, Dong‐Qing Wei, Shuangjun Lin, Yi Xiong

ProStab predicts protein stability changes upon mutations using a deep learning framework combining sequence and structure information, showing strong performance and experimental validation.

bioRxiv · Aug 11, 2025 · PreprintBioinformatics

Target-specific design of drug-like PPI inhibitors via hot-spot-guided generative deep learning

Heqi Sun, Jiayi Li, Yufang Zhang, Shenggeng Lin, Junwei Chen, Hong‐Zhou Tan, Ruixuan Wang, Xueying Mao, Jianwei Zhao, Rongpei Li, Yi Xiong, Dong‐Qing Wei

This paper introduces Hot2Mol, a deep learning framework for designing drug-like PPI inhibitors by generating molecules that mimic hot-spot residues, showing improved performance over baselines.

bioRxiv · Oct 29, 2024 · PreprintBioinformatics

A Self-attention Graph Convolutional Network for Precision Multi-tumour Early Diagnostics with DNA Methylation Data

Xue Jiang, Zhiqi Li, Heng Wang, Qiankun Wang, Yanyi Chu, Xueying Mao, Jing Ying Zhao, Mingming Jiang, Bowen Zhao, Guanning Lin, Edwin Wang, Dong‐Qing Wei

The paper introduces a self-attention graph convolutional network to identify key DNA methylation sites for multi-tumor early diagnostics, achieving improved sensitivity in blood-based detection.

bioRxiv · Feb 11, 2022 · PreprintBioinformatics