Author

Jianwei Zhao

Shanghai Jiao Tong UniversityORCID 0000-0001-9566-2178Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Dong‐Qing WeiiD· 1 shared Heqi SuniD· 1 shared Hong‐Zhou TaniD· 1 shared Jiayi LiiD· 1 shared Junwei CheniD· 1 shared Rongpei LiiD· 1 shared Ruixuan WangiD· 1 shared Shenggeng LiniD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioinformatics

Dong‐Qing WeiORCID

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1 paper

Recent·Most cited

Target-specific design of drug-like PPI inhibitors via hot-spot-guided generative deep learning

Heqi Sun, Jiayi Li, Yufang Zhang, Shenggeng Lin, Junwei Chen, Hong‐Zhou Tan, Ruixuan Wang, Xueying Mao, Jianwei Zhao, Rongpei Li, Yi Xiong, Dong‐Qing Wei

This paper introduces Hot2Mol, a deep learning framework for designing drug-like PPI inhibitors by generating molecules that mimic hot-spot residues, showing improved performance over baselines.

bioRxiv · Oct 29, 2024 · PreprintBioinformatics