SMCHD1 compacts DNA directly in an ATP-regulated manner
J.D. Ng, Xiaodan Zhao, Xuyao Liu, Aghil Soman, Lars Nordenskiöld, Jie Yan, Shifeng Xue
This study shows SMCHD1 directly compacts DNA in a flexible, ATP-independent manner, forming clusters that may contribute to gene silencing and genome organization.
bioRxiv · Jul 8, 2025 · PreprintMolecular Biology