Single-cell Landscape of T Cell Heterogeneity in Kawasaki Disease: STAT3/JAK Axis Regulates the Lineage Differentiation Bias of Th17 Cells
Sirui Song, Yanfang Zong, Yanbing Xu, Liqin Chen, Y P Zhou, Le Chen, Guang Li, Tingting Xiao, Min Huang
The paper uses scRNA-seq to analyze T-cell subtypes in Kawasaki disease, identifying a Th17 differentiation bias regulated by the STAT3/JAK axis during acute inflammation.
bioRxiv · Mar 23, 2026 · PreprintBioinformatics